BDBM22791 2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetic acid::Isatin-based compound, 11

SMILES OC(=O)CN1C(=O)C(=O)c2ccccc12

InChI Key InChIKey=KYAMYNWIAQNFEG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 22791   

TargetLiver carboxylesterase 1(Human)
St. Jude Research Hospital

LigandPNGBDBM22791(2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetic acid...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
St. Jude Research Hospital

LigandPNGBDBM22791(2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetic acid...)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.45kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetCholinesterase(Human)
St. Jude Research Hospital

LigandPNGBDBM22791(2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetic acid...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
St. Jude Research Hospital

LigandPNGBDBM22791(2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetic acid...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Rabbit)
St. Jude Research Hospital

LigandPNGBDBM22791(2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetic acid...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed