BDBM23559 3-Carboxamide-coumarin deriv., 29::6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-carboxamide

SMILES Cc1cccc(NC(=O)c2cc3cc(C)ccc3oc2=O)c1

InChI Key InChIKey=BYMDGQZMHMAQIC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23559   

TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23559(6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23559(6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataIC50: 1.00E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Namur

LigandPNGBDBM23559(6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataIC50: 5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of Namur

LigandPNGBDBM23559(6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Namur

LigandPNGBDBM23559(6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Namur

LigandPNGBDBM23559(6-methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-ca...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed