BDBM23569 (2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-3-phenyl-2-[(2R)-pyrrolidin-2-ylformamido]propanamide::D-Pro-Phe-Arg chloromethyl ketone (PCK)

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H]-1-[#6]-[#6]-[#6]-[#7]-1)-[#6](=O)-[#6]Cl

InChI Key InChIKey=KSAWJQXHHNRNMK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23569   

TargetPlasma kallikrein(Human)
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50: 31nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50: 180nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50: 1.50E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50: 1.90E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50: 2.50E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed