BDBM260901 US9540323, 92::US9540323, 98::US9540323, example 98

SMILES CC1(C)CN(c2c1c(ccc2O)-c1nc2ccc(F)cc2o1)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=AQPUDLXYSUGWMQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260901   

TargetP2Y purinoceptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM260901(US9540323, 92 | US9540323, 98 | US9540323, example...)
Affinity DataKi:  27nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent

TargetP2Y purinoceptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM260901(US9540323, 92 | US9540323, 98 | US9540323, example...)
Affinity DataKi:  37nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent