BDBM261033 US9540323, 254::US9540323, example 254

SMILES CC(C)(C)c1nc(co1)-c1c2c(N(CC2(C)C)c2ccccc2NC(=O)Nc2nc3ccc(F)cc3s2)c(O)cc1F

InChI Key InChIKey=BRHYZZPVWGYGKV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261033   

TargetP2Y purinoceptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM261033(US9540323, 254 | US9540323, example 254)
Affinity DataKi:  14nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent