BDBM26587 2-{[3-(1-carboxyethoxy)-9-oxo-8-oxatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2(7),3,5,10,12-hexaen-5-yl]oxy}propanoic acid::H1-A1NI2, 12

SMILES CC(Oc1cc(OC(C)C(O)=O)c2c(c1)oc(=O)c1ccccc21)C(O)=O

InChI Key InChIKey=UZFGLYBIRURIOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26587   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandPNGBDBM26587(2-{[3-(1-carboxyethoxy)-9-oxo-8-oxatricyclo[8.4.0....)
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed