BDBM26671 3-{[4-(2,4-dihydroxyphenyl)-1,3-thiazol-2-yl]amino}benzoic acid::thiazoleamino benzoic acid, 4

SMILES OC(=O)c1cccc(Nc2nc(cs2)-c2ccc(O)cc2O)c1

InChI Key InChIKey=OSICASGPBKFBQV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26671   

TargetSerine/threonine-protein kinase pim-1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM26671(3-{[4-(2,4-dihydroxyphenyl)-1,3-thiazol-2-yl]amino...)
Affinity DataKi:  3.40E+3nM ΔG°:  -7.58kcal/molepH: 7.6 T: 2°CAssay Description:A coupled-enzyme assay was used to quantify the ADP generated in the kinase reaction with S6 peptide (RRRLSSLRA) as the phosphoacceptor substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed