BDBM26686 6-(4-chlorophenyl)-4-oxo-9-oxa-3-azatricyclo[8.4.0.0^{2,7}]tetradeca-1(10),2(7),5,11,13-pentaene-5-carbonitrile::cid_399090::pyridone-based compound, 14

SMILES Clc1ccc(cc1)-c1c2COc3ccccc3-c2[nH]c(=O)c1C#N

InChI Key InChIKey=ORBJBHORENRNCH-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26686   

TargetSerine/threonine-protein kinase pim-1(Human)
Valeant Pharmaceuticals Research and Development

LigandPNGBDBM26686(cid_399090 | 6-(4-chlorophenyl)-4-oxo-9-oxa-3-azat...)
Affinity DataIC50: 920nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM26686(cid_399090 | 6-(4-chlorophenyl)-4-oxo-9-oxa-3-azat...)
Affinity DataEC50:  5.30E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM26686(cid_399090 | 6-(4-chlorophenyl)-4-oxo-9-oxa-3-azat...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay