BDBM26694 6-(4-fluorophenyl)-4-oxo-9-thia-3-azatricyclo[8.4.0.0^{2,7}]tetradeca-1(10),2(7),5,11,13-pentaene-5-carbonitrile::pyridone-based compound, 22

SMILES Fc1ccc(cc1)-c1c2CSc3ccccc3-c2[nH]c(=O)c1C#N

InChI Key InChIKey=BJVKUBOMYHLBHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26694   

TargetSerine/threonine-protein kinase pim-1(Human)
Valeant Pharmaceuticals Research and Development

LigandPNGBDBM26694(6-(4-fluorophenyl)-4-oxo-9-thia-3-azatricyclo[8.4....)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed