BDBM26894 3-(cyclopropylmethyl)-8-(diphenylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::spiropiperidine analogue, 15

SMILES O=C1N(CC2CC2)CN(c2ccccc2)C11CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=DFUWOFTVSMOGGO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26894   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26894(3-(cyclopropylmethyl)-8-(diphenylmethyl)-1-phenyl-...)
Affinity DataKi:  83nM ΔG°:  -9.56kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26894(3-(cyclopropylmethyl)-8-(diphenylmethyl)-1-phenyl-...)
Affinity DataKi:  633nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26894(3-(cyclopropylmethyl)-8-(diphenylmethyl)-1-phenyl-...)
Affinity DataKi:  5.28E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26894(3-(cyclopropylmethyl)-8-(diphenylmethyl)-1-phenyl-...)
Affinity DataKi:  5.41E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2009
Entry Details Article
PubMed