BDBM29968 arylpyrazole, 13

SMILES Cc1c(CNC2CCCC2)nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=AFZGUFJUAJQREI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29968   

LigandPNGBDBM29968(arylpyrazole, 13)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:Binding affinity to the hERG K+ channel was measured by displacement of [35S]-radiolabeled MK499 in membranes derived from HEK 293 cells stably trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Pharmaceutical

LigandPNGBDBM29968(arylpyrazole, 13)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Pharmaceutical

LigandPNGBDBM29968(arylpyrazole, 13)
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed