BDBM31835 2,4-Bisanilinopyrimidine, 14

SMILES Oc1ccc(Nc2ncc(F)c(Nc3ccc(cc3)C(=O)NC3CC3)n2)cc1

InChI Key InChIKey=MOVLGZOUINJGGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31835   

TargetAurora kinase A(Human)
Genentech

LigandPNGBDBM31835(2,4-Bisanilinopyrimidine, 14)
Affinity DataIC50: 54nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandPNGBDBM31835(2,4-Bisanilinopyrimidine, 14)
Affinity DataIC50: 3.80E+3nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed