BDBM32915 2-keto-3,4-dimethyl-6-(3-thienyl)-1,6-dihydropyrimidine-5-carboxylic acid 2-phenoxyethyl ester::2-phenoxyethyl 1,6-dimethyl-2-oxo-4-thien-3-yl-1,2,3,4-tetrahydropyrimidine-5-carboxylate::2-phenoxyethyl 3,4-dimethyl-2-oxidanylidene-6-thiophen-3-yl-1,6-dihydropyrimidine-5-carboxylate::2-phenoxyethyl 3,4-dimethyl-2-oxo-6-thiophen-3-yl-1,6-dihydropyrimidine-5-carboxylate::3,4-dimethyl-2-oxo-6-(3-thiophenyl)-1,6-dihydropyrimidine-5-carboxylic acid 2-phenoxyethyl ester::MLS000728695::SMR000306974::cid_545021

SMILES CN1C(=O)NC(c2ccsc2)C(C(=O)OCCOc2ccccc2)=C1C

InChI Key InChIKey=UPBVAOGORDOJLD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32915   

TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32915(2-phenoxyethyl 3,4-dimethyl-2-oxo-6-thiophen-3-yl-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetSolute carrier family 12 member 5(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM32915(2-phenoxyethyl 3,4-dimethyl-2-oxo-6-thiophen-3-yl-...)
Affinity DataEC50:  6.12E+4nMAssay Description:Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay