BDBM37519 5-Piperidin-1-ylmethyl-furan-2-carboxylic acid (4-fluoro-benzyl)-[1-(3-methyl-butylcarbamoyl)-ethyl]-amide::MLS000034063::N-(4-fluorobenzyl)-N-[2-(isoamylamino)-2-keto-1-methyl-ethyl]-5-(piperidinomethyl)-2-furamide::N-[(4-fluorophenyl)methyl]-N-[1-(3-methylbutylamino)-1-oxidanylidene-propan-2-yl]-5-(piperidin-1-ylmethyl)furan-2-carboxamide::N-[(4-fluorophenyl)methyl]-N-[1-(3-methylbutylamino)-1-oxopropan-2-yl]-5-(1-piperidinylmethyl)-2-furancarboxamide::N-[(4-fluorophenyl)methyl]-N-[1-(3-methylbutylamino)-1-oxopropan-2-yl]-5-(piperidin-1-ylmethyl)furan-2-carboxamide::SMR000002692::cid_644939

SMILES CC(C)CCNC(=O)C(C)N(Cc1ccc(F)cc1)C(=O)c1ccc(CN2CCCCC2)o1

InChI Key InChIKey=SDEKEKLLLPTMQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37519   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37519(N-[(4-fluorophenyl)methyl]-N-[1-(3-methylbutylamin...)
Affinity DataIC50: 8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay