BDBM40957 5,8-bis(chloranyl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one::5,8-dichloro-2,3,4,9-tetrahydro-beta-carbolin-1-one::5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one::MLS000080441::SMR000034527::cid_665194

SMILES c1cc(c2c(c1Cl)c3c([nH]2)C(=O)NCC3)Cl

InChI Key InChIKey=VJUGVVOGVWAGRV-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 40957   

TargetFocal adhesion kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40957(5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2011
Entry Details
PCBioAssay
TargetProtein-tyrosine kinase 2-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40957(5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-...)
Affinity DataIC50: 1.02E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM40957(5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-...)
Affinity DataIC50: 4.78E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay