BDBM491438 US10975056, Example 412

SMILES CCc1c(c(nc(c1C#N)S[C@H](c2ccccc2)C(=O)N)N3CCC(CC3)N)C#N

InChI Key InChIKey=KNKHRZYILDZLRE-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491438   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491438(US10975056, Example 412)
Affinity DataIC50: 320nMAssay Description:Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)