BDBM49608 3-(4-Biphenyl-4-yl-thiazol-2-ylamino)-6,7-dimethoxy-3H-isobenzofuran-1-one::6,7-dimethoxy-3-[[4-(4-phenylphenyl)-1,3-thiazol-2-yl]amino]-3H-2-benzofuran-1-one::6,7-dimethoxy-3-[[4-(4-phenylphenyl)-2-thiazolyl]amino]-3H-isobenzofuran-1-one::6,7-dimethoxy-3-[[4-(4-phenylphenyl)thiazol-2-yl]amino]phthalide::MLS000588041::SMR000220040::cid_3792553

SMILES COc1ccc2C(Nc3nc(cs3)-c3ccc(cc3)-c3ccccc3)OC(=O)c2c1OC

InChI Key InChIKey=SFXWYBRACHQPMR-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 49608   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49608(SMR000220040 | 6,7-dimethoxy-3-[[4-(4-phenylphenyl...)
Affinity DataEC50:  2.98E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49608(SMR000220040 | 6,7-dimethoxy-3-[[4-(4-phenylphenyl...)
Affinity DataIC50: 6.08E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetCysteine protease ATG4B(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49608(SMR000220040 | 6,7-dimethoxy-3-[[4-(4-phenylphenyl...)
Affinity DataIC50: 8.28E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetPhospholipase A2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49608(SMR000220040 | 6,7-dimethoxy-3-[[4-(4-phenylphenyl...)
Affinity DataIC50: 1.71E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetProtein skinhead-1(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49608(SMR000220040 | 6,7-dimethoxy-3-[[4-(4-phenylphenyl...)
Affinity DataIC50: 3.38E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay