BDBM50001815 1-(2-{4-[3-(4-Fluoro-phenyl)-5-trifluoromethyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL355917

SMILES Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F

InChI Key InChIKey=PNJBDZLOVISXIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001815   

TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001815(CHEMBL355917 | 1-(2-{4-[3-(4-Fluoro-phenyl)-5-trif...)
Affinity DataIC50: 9.30nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001815(CHEMBL355917 | 1-(2-{4-[3-(4-Fluoro-phenyl)-5-trif...)
Affinity DataIC50: 190nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001815(CHEMBL355917 | 1-(2-{4-[3-(4-Fluoro-phenyl)-5-trif...)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [3H]spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed