BDBM50003995 CHEMBL2180009

SMILES COc1cn(nc(-c2ccnn2-c2ccccc2)c1=O)-c1ccccc1F

InChI Key InChIKey=JBXPBSYUHPMEHH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003995   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50003995(CHEMBL2180009)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of human full length PDE10A expressed in SF21 cells using [3H]cGMP as substrate after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50003995(CHEMBL2180009)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/20/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL