BDBM50005834 1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-acetyl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL38041

SMILES CC(C)n1c2ccccc2n(C(=O)CC2CC3CCC(C2)N3C)c1=O

InChI Key

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50005834   

LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50005834(CHEMBL38041 | 1-Isopropyl-3-[2-(8-methyl-8-aza-bic...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain corticesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed