BDBM50007329 (R)-2-[(R)-2-(2-{2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(all-D-[Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL15595::[Leu5] enkephalin

SMILES CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](N)Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=URLZCHNOLZSCCA-UHFFFAOYSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50007329   

TargetDelta-type opioid receptor(Rat)
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 0.600nMAssay Description:Binding affinity against rat Opioid receptor delta 1 expressed in CHO cells determined by competitive inhibition of 1 nM [3H]DPDPE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity against rat mu-opioid receptor expressed in CHO cells by competitive inhibition of 1 nM [3H]DAMGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]DSLET from rat brain membrane opioid receptor deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [3H]DSLET binding to rat brain membrane Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]DAGO from rat brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity towards Opioid receptor mu 1 in rat brain membrane using [3H]DAGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity towards delta Opioid receptor using guinea pig ileum (GPI) assay was determined for the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 246nMAssay Description:Inhibitory activity towards Opioid receptor mu 1 using guinea pig ileum (GPI) assay was determined for the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Institute For Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50007329(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50: 400nMAssay Description:Binding affinity against rat kappa-opioid receptor expressed in CHO cells was determined by competitive inhibition of 2 nM [3H]-U 69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed