BDBM50007401 1-Phenyl-4-(4-phenyl-butyl)-piperazine::CHEMBL85879

SMILES C(CCc1ccccc1)CN1CCN(CC1)c1ccccc1

InChI Key InChIKey=BGDZXIKVCVQJFR-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50007401   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataKi:  1nMAssay Description:Tested for binding affinity against 5-hydroxytryptamine 1A receptor from rat frontal cortical regions using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataKi:  2.60nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataIC50: 45nMAssay Description:Compound was tested for its binding affinity towards dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataIC50: 2.82E+3nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007401(CHEMBL85879 | 1-Phenyl-4-(4-phenyl-butyl)-piperazi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its affinity towards PCP receptor in rat brain membrane [3H]MK-801 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed