BDBM50008705 CHEMBL168418::N-Benzyl-2-phenoxy-nicotinamide

SMILES O=C(NCc1ccccc1)c1cccnc1Oc1ccccc1

InChI Key InChIKey=WKEHRSGEQPYYPS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008705   

LigandPNGBDBM50008705(CHEMBL168418 | N-Benzyl-2-phenoxy-nicotinamide)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50008705(CHEMBL168418 | N-Benzyl-2-phenoxy-nicotinamide)
Affinity DataIC50: 3.16E+3nMAssay Description:Negative log of inhibitory concentration determined against c-Jun N-terminal kinase (Activity reported against the isolated JNK-1 enzyme)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50008705(CHEMBL168418 | N-Benzyl-2-phenoxy-nicotinamide)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of [3H]rolipram binding to rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2019
Entry Details Article
PubMed