BDBM50017074 2-(3,4-Dichloro-phenyl)-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-acetamide::CHEMBL25493

SMILES CN1CCC[C@@]11CCCC[C@@H]1NC(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ACJWWDOSBNCLFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017074   

TargetMu-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017074(CHEMBL25493 | 2-(3,4-Dichloro-phenyl)-N-(1-methyl-...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against Opioid receptor mu 1 of guinea pig brain using [3H]DAG0 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017074(CHEMBL25493 | 2-(3,4-Dichloro-phenyl)-N-(1-methyl-...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity against Opioid receptor delta 1 of guinea pig was determined by using [3H]DADLE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017074(CHEMBL25493 | 2-(3,4-Dichloro-phenyl)-N-(1-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding inhibition against Opioid receptor kappa 1 of guinea pig was determined using [3H]ethylketocyclazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed