BDBM50020498 5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine::CHEMBL30560

SMILES COc1cccc2CC(N)CCc12

InChI Key InChIKey=SIHPGAYIYYGOIP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020498   

TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020498(CHEMBL30560 | 5-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  334nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020498(CHEMBL30560 | 5-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  683nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020498(CHEMBL30560 | 5-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi: >3.33E+4nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50020498(CHEMBL30560 | 5-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  1.57E+5nMAssay Description:The compound was tested for In vitro inhibitory activity against Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed