BDBM50054740 1-(2-Benzhydryloxy-ethyl)-piperazine::CHEMBL142522

SMILES C(CN1CCNCC1)OC(c1ccccc1)c1ccccc1

InChI Key InChIKey=MBFDHHKTIBKZNR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054740   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054740(1-(2-Benzhydryloxy-ethyl)-piperazine | CHEMBL14252...)
Affinity DataIC50: 110nMAssay Description:Binding affinity against dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054740(1-(2-Benzhydryloxy-ethyl)-piperazine | CHEMBL14252...)
Affinity DataIC50: 124nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054740(1-(2-Benzhydryloxy-ethyl)-piperazine | CHEMBL14252...)
Affinity DataIC50: 1.48E+3nMAssay Description:Binding affinity against sigma receptor using radioligand ([3H](+)-pentazocine) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054740(1-(2-Benzhydryloxy-ethyl)-piperazine | CHEMBL14252...)
Affinity DataIC50: 9.57E+3nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed