BDBM50067275 4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-phenyl-benzamide::CHEMBL133005

SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(cc1)C(=O)Nc1ccccc1)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl

InChI Key InChIKey=FCQLMFHZIIBJMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067275   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067275(4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-y...)
Affinity DataIC50: 6.30nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Guinea pig)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067275(4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-y...)
Affinity DataIC50: 6.30nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed