BDBM50068749 4'-Isobutyl-biphenyl-2-sulfonic acid (4,6-dimethoxy-pyrimidin-2-yl)-amide::CHEMBL356972

SMILES COc1cc(OC)nc(NS(=O)(=O)c2ccccc2-c2ccc(CC(C)C)cc2)n1

InChI Key InChIKey=DMDOZLAWJSQBRQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068749   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068749(4'-Isobutyl-biphenyl-2-sulfonic acid (4,6-dimethox...)
Affinity DataKi:  3.90E+3nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068749(4'-Isobutyl-biphenyl-2-sulfonic acid (4,6-dimethox...)
Affinity DataKi:  5.00E+4nMAssay Description:Ability to inhibit binding of [125I]-ET-1 to membranes prepared from A10 rat cerebellum (Endothelin B receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed