BDBM50072453 3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahydro-2H-benzo[g]isoquinolin-4a-yl)-phenol::CHEMBL324681

SMILES CN1CC[C@@]2(Cc3ccccc3C[C@]2(C)C1)c1cccc(O)c1

InChI Key InChIKey=POUJDAQKDOGDRQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50072453   

TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50072453(3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahy...)
Affinity DataKi:  53nMAssay Description:Compound was tested for the inhibition of [35S]GTP-gamma-S, binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50072453(3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahy...)
Affinity DataKi:  119nMAssay Description:Binding affinity was determined against Mu opioid receptor using [3H]naltrexone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50072453(3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahy...)
Affinity DataKi:  166nMAssay Description:Binding affinity was determined as ability to displace [3H]-U-69, radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50072453(3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahy...)
Affinity DataKi:  222nMAssay Description:Compound was tested for the inhibition of [35S]GTP-gamma-S, binding in Guinea pig Caudate stimulated by the Opioid receptor delta 1 agonist Delta-SNC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50072453(3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahy...)
Affinity DataKi:  297nMAssay Description:Binding affinity was determined as ability to displace [3H]DAMGO radioligand from Mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50072453(3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahy...)
Affinity DataKi: >5.71E+3nMAssay Description:Binding affinity was determined as ability to displace [3H]DADLE radioligand from Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed