BDBM50074610 CHEMBL170339::[3-(4-Methoxy-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine

SMILES COc1ccc(cc1)C1C2CCC(CC2)C1CN(C)C

InChI Key InChIKey=LSNHNHXRKOSNAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50074610   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50074610([3-(4-Methoxy-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl...)
Affinity DataIC50: 380nMAssay Description:Inhibitory binding activity against rat striatal tissue using [3H]WIN-35248 as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50074610([3-(4-Methoxy-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of dopamine uptake into rat striatal tissue, using [3H]- dopamine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed