BDBM50075516 2-Allyloxyamino-5-[1-(3,5-di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)-ylidene]-thiazol-4-one::CHEMBL16127

SMILES CC(C)(C)c1cc(C=C2SC(NOCC=C)=NC2=O)cc(c1O)C(C)(C)C

InChI Key InChIKey=VOOYURWLZHBICA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075516   

TargetProstaglandin G/H synthase 2(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075516(2-Allyloxyamino-5-[1-(3,5-di-tert-butyl-4-hydroxy-...)
Affinity DataIC50: 1.60E+3nMAssay Description:IC50 value was determined against Prostaglandin G/H synthase 2 of J7744A.1 cell lines.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075516(2-Allyloxyamino-5-[1-(3,5-di-tert-butyl-4-hydroxy-...)
Affinity DataIC50: 2.70E+3nMAssay Description:IC50 against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075516(2-Allyloxyamino-5-[1-(3,5-di-tert-butyl-4-hydroxy-...)
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 value was determined against Prostaglandin G/H synthase 1 of human platelet rich plasma; Not activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed