BDBM50076009 16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-methoxy-3-methyl-(1S,14R,15R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-11-ol::CHEMBL169552

SMILES CO[C@@]12CCC3(C[C@H]1[C@@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2C3(CCN1C)c45

InChI Key InChIKey=APFIBTMKZJWVHH-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50076009   

TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards human mu opioid receptor in CHO cells using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity towards human delta opioid receptor in CHO cells using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataEC50:  1.20nMAssay Description:Activity was evaluated in human mu opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataEC50:  2.40nMAssay Description:Binding affinity towards human kappa opioid receptor in CHO cells using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity towards human kappa opioid receptor in CHO cells using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataEC50:  5nMAssay Description:Activity was evaluated in human delta opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed