BDBM50077341 4-(3,4-Dimethyl-7-oxo-7H-isoxazolo[3,4-d]pyridazin-6-yl)-butyric acid::CHEMBL292602

SMILES Cc1onc2c1c(C)nn(CCCC(O)=O)c2=O

InChI Key InChIKey=KBIUGAWOZQXNTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077341   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50077341(4-(3,4-Dimethyl-7-oxo-7H-isoxazolo[3,4-d]pyridazin...)
Affinity DataIC50: 6.51E+4nMAssay Description:In vitro inhibitory activity against Aldose reductase 2 obtained from calf lensesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed