BDBM50077356 (E)-4-(3-Methyl-7-oxo-4-phenyl-7H-isoxazolo[3,4-d]pyridazin-6-yl)-but-2-enoic acid::CHEMBL55475

SMILES Cc1onc2c1c(nn(C\C=C\C(O)=O)c2=O)-c1ccccc1

InChI Key InChIKey=JAHCDYJCCJGKRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077356   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50077356((E)-4-(3-Methyl-7-oxo-4-phenyl-7H-isoxazolo[3,4-d]...)
Affinity DataIC50: 1.07E+5nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) obtained from calf lensesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed