BDBM50081093 CHEMBL88079::N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2-(2-oxo-3-phenylmethanesulfonylamino-3,4-dihydro-2H-quinolin-1-yl)-acetamide; TFA

SMILES NC(=N)N1CCC[C@H](NC(=O)CN2C(=O)C(Cc3ccccc23)NS(=O)(=O)Cc2ccccc2)C1O

InChI Key InChIKey=GYZAJGLGNWNLGL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50081093   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory activity against human enzyme thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 289nMAssay Description:In vitro evaluation of inhibition of cleavage of the chromogenic substrate by human enzyme trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against human prothrombinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against human enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed