BDBM50082483 CHEMBL337761::{2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1,2,3,4-tetrahydro-isoquinolin-3-yl}-oxo-acetic acid

SMILES CN(C)c1ccc(Oc2ccc(cc2)S(=O)(=O)N2Cc3ccccc3CC2C(=O)C(O)=O)cc1

InChI Key InChIKey=XIMLFZSNGXTRSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082483   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082483({2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082483({2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed