BDBM50082892 6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol::CHEMBL436211

SMILES CN(C)C1C2CCC(CC2O)C1c1ccccc1

InChI Key

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50082892   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 7.04E+3nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 7.04E+3nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 7.23E+3nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 7.73E+3nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 7.73E+3nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 8.38E+3nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 9.92E+3nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 1.23E+4nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 1.23E+4nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 3.44E+4nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50082892(6-Dimethylamino-5-phenyl-bicyclo[2.2.2]octan-2-ol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed