BDBM50084486 CHEMBL92713::N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-3-methoxy-benzamide

SMILES COc1cccc(c1)C(=O)NCCCN1CCN(CC1)c1ccc(Cl)cc1

InChI Key InChIKey=AECUHGGFVKDBMH-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50084486   

TargetD(4) dopamine receptor(Human)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084486(N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  5.40nMAssay Description:In vitro binding affinity at human Dopamine receptor D4.4 by [3H]YM-09151-2 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084486(N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084486(N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  586nMAssay Description:Binding affinity towards Dopamine receptor D3 of rat using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084486(N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi: >850nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine receptor 1A receptor in rat hippocampal membranes by [3H]8-OH-DPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084486(N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi: >850nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084486(N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  3.95E+3nMAssay Description:In vitro binding affinity at human Dopamine receptor D2 (long) by [3H]spiroperidol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Universitá

Curated by ChEMBL
LigandPNGBDBM50084486(N-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  3.96E+3nMAssay Description:Binding affinity towards human Dopamine receptor D2 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed