BDBM50089040 CHEMBL17483::N*2*,N*4*-Diphenyl-quinazoline-2,4-diamine

SMILES N(c1ccccc1)c1nc(Nc2ccccc2)c2ccccc2n1

InChI Key InChIKey=VNPWQZPLOBAPPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089040   

TargetNeuropeptide Y receptor type 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089040(N*2*,N*4*-Diphenyl-quinazoline-2,4-diamine | CHEMB...)
Affinity DataIC50: 80nMAssay Description:Compound was tested for its affinity to bind with Neuropeptide Y receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Minas Gerais (Ufmg)

Curated by ChEMBL
LigandPNGBDBM50089040(N*2*,N*4*-Diphenyl-quinazoline-2,4-diamine | CHEMB...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed