BDBM50097430 CHEMBL164087::N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamide

SMILES O=C(Nc1nc(cs1)-c1ccccn1)c1ccccc1

InChI Key InChIKey=NNBHDRDMPNNEKO-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097430   

TargetAdenosine receptor A1(Rat)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50097430(N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamide | CHEMBL...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]DPCPX binding to adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50097430(N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamide | CHEMBL...)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50097430(N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamide | CHEMBL...)
Affinity DataKi:  8.70E+3nMAssay Description:Displacement of [3H]-CGS-21,680 or [3H]ZM-241385 binding in adenosine A2A receptor of rat striatal membrane was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50097430(N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamide | CHEMBL...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50097430(N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamide | CHEMBL...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50097430(N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamide | CHEMBL...)
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed