BDBM50099711 CHEMBL38066::Naphtho[1,2-b]furan-4,5-dione

SMILES O=C1c2ccoc2-c2ccccc2C1=O

InChI Key InChIKey=HAUHEECDQLXVSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099711   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099711(Naphtho[1,2-b]furan-4,5-dione | CHEMBL38066)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099711(Naphtho[1,2-b]furan-4,5-dione | CHEMBL38066)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099711(Naphtho[1,2-b]furan-4,5-dione | CHEMBL38066)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed