BDBM50104367 4-[2-(4-Bromo-phenyl)-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL87588

SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccc(Br)cc1

InChI Key InChIKey=NCECUPUQFBKLMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104367   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104367(4-[2-(4-Bromo-phenyl)-5-(4-fluoro-phenyl)-3H-imida...)
Affinity DataIC50: 160nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50104367(4-[2-(4-Bromo-phenyl)-5-(4-fluoro-phenyl)-3H-imida...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article

TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50104367(4-[2-(4-Bromo-phenyl)-5-(4-fluoro-phenyl)-3H-imida...)
Affinity DataIC50: 270nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50104367(4-[2-(4-Bromo-phenyl)-5-(4-fluoro-phenyl)-3H-imida...)
Affinity DataIC50: 2.90E+3nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed