BDBM50104962 CHEMBL325048::N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobutyl-succinamide

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key InChIKey=ZYIMYAJZHPOFQU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104962   

TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  37nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  73nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  82nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  162nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed