BDBM50108776 4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-c]azepin-8-one::CHEMBL359106

SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c(Br)cc12

InChI Key InChIKey=ATBAETXFFCOZOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108776   

TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108776(4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50108776(4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed