BDBM50110992 8-{4-[2-(4-Benzyl-piperazin-1-yl)-2-oxo-ethoxy]-phenyl}-1-butyl-3,7-dihydro-purine-2,6-dione::CHEMBL38304

SMILES CCCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(OCC(=O)N2CCN(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=AARZBDDJPFYPSG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50110992   

TargetAdenosine receptor A2b(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50110992(8-{4-[2-(4-Benzyl-piperazin-1-yl)-2-oxo-ethoxy]-ph...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50110992(8-{4-[2-(4-Benzyl-piperazin-1-yl)-2-oxo-ethoxy]-ph...)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]CCPA binding to rat adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50110992(8-{4-[2-(4-Benzyl-piperazin-1-yl)-2-oxo-ethoxy]-ph...)
Affinity DataKi:  122nMAssay Description:Inhibition of [3H]CCPA binding to human recombinant Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50110992(8-{4-[2-(4-Benzyl-piperazin-1-yl)-2-oxo-ethoxy]-ph...)
Affinity DataKi:  475nMAssay Description:Inhibition of [3H]PSB-11 binding to human Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50110992(8-{4-[2-(4-Benzyl-piperazin-1-yl)-2-oxo-ethoxy]-ph...)
Affinity DataKi:  550nMAssay Description:Inhibition of [3H]MSX-2 binding to rat adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed