BDBM50118330 1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-[4-(1H-indol-4-yl)-piperazin-1-yl]-propan-1-ol;::CHEMBL135623

SMILES OC(CCN1CCN(CC1)c1cccc2[nH]ccc12)c1csc2ccc(F)cc12

InChI Key InChIKey=GWCXMTRMKIIFDL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118330   

Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118330(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-[4-(1H-indol-...)
Affinity DataKi:  5.90nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118330(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-[4-(1H-indol-...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118330(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-[4-(1H-indol-...)
Affinity DataIC50: 16.1nMAssay Description:Inhibition of (+)-8-OH-DPAT stimulated [35S]GTP-gamma-S, binding to 5-hydroxytryptamine 1A receptor in hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed