BDBM50119074 CHEMBL95774::N-[4-(3-Chloro-4-fluoro-phenylamino)-3-cyano-7-(3-morpholin-4-yl-propoxy)-quinolin-6-yl]-acrylamide

SMILES Fc1ccc(Nc2c(cnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)C#N)cc1Cl

InChI Key InChIKey=FODAAEGGNDJNFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119074   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119074(N-[4-(3-Chloro-4-fluoro-phenylamino)-3-cyano-7-(3-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119074(N-[4-(3-Chloro-4-fluoro-phenylamino)-3-cyano-7-(3-...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed