BDBM50123073 1-(4-Fluoro-phenyl)-4-{4-[2-(1H-indol-3-yl)-ethyl]-piperidin-1-yl}-butan-1-one::CHEMBL423706

SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CCc2c[nH]c3ccccc23)CC1

InChI Key InChIKey=DLNHKFQPIHQHPC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123073   

TargetSodium-dependent serotonin transporter(Rat)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50123073(1-(4-Fluoro-phenyl)-4-{4-[2-(1H-indol-3-yl)-ethyl]...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]paroxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50123073(1-(4-Fluoro-phenyl)-4-{4-[2-(1H-indol-3-yl)-ethyl]...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed