BDBM50123634 CHEMBL3622731

SMILES C\C=C1/NC(=O)c2csc(CNC(=O)C[C@H](OC(=O)[C@@H](NC1=O)C(C)C)\C=C\CCSC(C)=O)n2

InChI Key InChIKey=AJEJWONOGKARDP-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50123634   

TargetHistone deacetylase 1(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human HDAC1 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human HDAC3 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 328nMAssay Description:Inhibition of recombinant human HDAC2 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 751nMAssay Description:Inhibition of recombinant human HDAC10 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of recombinant human HDAC6 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC5 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC9 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC7 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC11 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Guangzhou Institute of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50123634(CHEMBL3622731)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed