BDBM50126064 (S)-1-((S)-3-Chloro-phenyl)-2-[2-(1H-indol-3-yl)-1-methyl-ethylamino]-ethanol::CHEMBL282039

SMILES C[C@@H](Cc1c[nH]c2ccccc12)NC[C@@H](O)c1cccc(Cl)c1

InChI Key InChIKey=AGWBMRMDTWHPJM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126064   

TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126064((S)-1-((S)-3-Chloro-phenyl)-2-[2-(1H-indol-3-yl)-1...)
Affinity DataEC50:  33nMAssay Description:Agonistic activity against human Beta-3 adrenergic receptor as cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126064((S)-1-((S)-3-Chloro-phenyl)-2-[2-(1H-indol-3-yl)-1...)
Affinity DataEC50:  140nMAssay Description:Agonistic activity against human Beta-1 adrenergic receptor by measuring cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126064((S)-1-((S)-3-Chloro-phenyl)-2-[2-(1H-indol-3-yl)-1...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonistic activity against human Beta-3 adrenergic receptor as cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed